Multivalent mannose-displaying nanoparticles constructed from poly{styrene-co-[(maleic anhydride)-alt-styrene]}.
نویسندگان
چکیده
Micellar mannose nanoparticles were constructed from poly{styrene-co-[(maleic anhydride)-alt-styrene]} with fluorophores or quenchers doped into the hydrophobic inner cores, allowing the direct monitoring of multivalent lectin-glycan interactions. The mannose-displaying nanoparticles bind Con A and sperm surface lectins with high affinity, suggesting their broad utility for modulating protein-carbohydrate interaction mediated cell surface biology.
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 7 10 شماره
صفحات -
تاریخ انتشار 2009